Karp´s Cell and Molecular Biology Concepts and Experiments – Gerald Karp – 9th Edition


La y Molecular de Karp ofrece una narración concisa e ilustrativa que ayuda a los estudiantes a conectar los conceptos clave y la experimentación, para que comprendan mejor cómo sabemos lo que sabemos en el mundo de la .

Este texto clásico explora los conceptos básicos con considerable profundidad, añadiendo a menudo detalles experimentales. Está escrito con un estilo atractivo y de longitud media, para ayudar a los estudiantes a manejar la plétora de detalles que se encuentran en el curso de Biología Celular.

La 9ª edición incluye dos nuevas secciones y una asociada en cada capítulo que muestran la relevancia de los conceptos clave de la biología celular para la biología celular vegetal y la bioingeniería.

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  • Chapter 1: Introduction to the Study of Cell and Molecular Biology
    1.1. The Discovery of Cells
    1.2. Basic Properties of Cells
    1.3. Two Fundamentally Different Classes of Cells
    1.4. Viruses and Viroids
    1.5. Green Cells: Volvox, an Experiment in Multicellularity
    1.6. Engineering Linkage: Tissue Engineering Analytic Questions

    Chapter 2: The Chemical Basis of Life
    2.1. Covalent Bonds
    2.2. Engineering Linkage: Radionuclides for Imaging and Treatment
    2.3. Noncovalent Bonds
    2.4. Acids, Bases, and Buffers
    2.5. The Nature of Biological Molecules
    2.6. Green Cells: Chemical Fertilizers
    2.7. Four Types of Biological Molecules
    2.8. The Formation of Complex Macromolecular Structures Analytic Questions

    Chapter 3: Bioenergetics, Enzymes, and Metabolism
    3.1. Bioenergetics
    3.2. Enzymes as Biological Catalysts
    3.3. Metabolism
    3.4. Green Cells: Regulation of Metabolism by the Light/Dark Cycle
    3.5. Engineering Linkage: Using Metabolism to Image Tumors Analytic Questions

    Chapter 4: The Structure and Function of the Plasma Membrane
    4.1. Introduction to the Plasma Membrane
    4.2. The Chemical Composition of Membranes
    4.3. Membrane Proteins
    4.4. Membrane Lipids and Membrane Fluidity
    4.5. The Dynamic Nature of the Plasma Membrane
    4.6. The Movement of Substances across Cell Membranes
    4.7. Membrane Potentials and Nerve Impulses
    4.8. Green Cells: Electrical Signaling in Plants
    4.9. Engineering Linkage: Neurotechnology Analytic Questions

    Chapter 5: Aerobic Respiration and the Mitochondrion
    5.1. Mitochondrial Structure and Function
    5.2. Aerobic Metabolism in the Mitochondrion
    5.3. The Role of Mitochondria in the Formation of ATP
    5.4. Engineering Linkage: Measuring Blood Oxygen
    5.5. Establishment of a Proton-Motive Force
    5.6. The Machinery for ATP Formation
    5.7. Peroxisomes
    5.8. Green Cells: Glyoxysomes Analytic Questions

    Chapter 6: Photosynthesis and the Chloroplast
    6.1. The Origin of Photosynthesis
    6.2. Chloroplast Structure
    6.3. An Overview of Photosynthetic Metabolism
    6.4. The Absorption of Light
    6.5. Green Cells: Chromoplasts
    6.6. Photosynthetic Units and Reaction Centers
    6.7. Photophosphorylation
    6.8. Carbon Dioxide Fixation and the Synthesis of Carbohydrate
    6.9. Engineering Linkage: Photodynamic Therapy Analytic Questions

    Chapter 7: Interactions Between Cells and Their Environment
    7.1. Extracellular Interactions
    7.2. Engineering Linkage: Organoids
    7.3. Interactions of Cells with Extracellular Materials
    7.4. Interactions of Cells with Other Cells
    7.5. Tight Junctions: Sealing the Extracellular Space
    7.6. Intercellular Communication
    7.7. Cell Walls
    7.8. Green Cells: Cell Walls and Plant Terrestrialization Analytic Questions

    Chapter 8: Cytoplasmic Membrane Systems: Structure, Function, and Membrane Traff...
    8.1. An Overview of the Endomembrane System
    8.2. A Few Approaches to the Study of Endomembranes
    8.3. The Endoplasmic Reticulum
    8.4. The Golgi Complex
    8.5. Types of Vesicle Transport
    8.6. Engineering Linkage: Extracellular Vesicles for Drug Delivery
    8.7. Lysosomes
    8.8 Green Cells: Plant Cell Vacuoles
    8.9. The Endocytic Pathway: Moving Membrane and Materials into the Cell Interior
    8.10. Posttranslational Uptake of Proteins by Peroxisomes, Mitochondria, and Chlo... Analytic Questions

    Chapter 9: The Cytoskeleton and Cell Motility
    9.1. Overview of the Major Functions of the Cytoskeleton
    9.2. Structure and Function of Microtubules
    9.3. Green Cells: Why the Woodbine Twineth
    9.4. Motor Proteins: Kinesins and Dyneins
    9.5. Microtubule-Organizing Centers (MTOCs)
    9.6. Structure and Function of Cilia and Flagella
    9.7. Intermediate Filaments
    9.8. Actin and Myosin
    9.9. Muscle Organization and Contraction
    9.10. Engineering Linkage: Muscle Biomechanics
    9.11. Actin-Binding Proteins
    9.12. Cellular Motility
    9.13. The Bacterial Cytoskeleton Analytic Questions

    Chapter 10: The Nature of the Gene and the Genome
    10.1. The Concept of a Gene as a Unit of Inheritance
    10.2. The Discovery of Chromosomes
    10.3. Chromosomes as the Carriers of Genetic Information
    10.4. The Chemical Nature of the Gene
    10.5. The Complexity of the Genome
    10.6. The Stability of the Genome
    10.7. Sequencing Genomes: The Footprints of Biological Evolution
    10.8. Engineering Linkage: Engineering Genomes
    10.9. The Genetic Basis of “Being Human”
    10.10. Green Cells: Gene Transfer by Agrobacterium tumefaciens Analytic Questions

    Chapter 11: The Central Dogma: DNA to RNA to Protein

    11.1. The Relationships among Genes, Proteins, and RNAs

    11.2. An Overview of Transcription in Both Prokaryotic and Eukaryotic Cells

    11.3. Synthesis and Processing of Eukaryotic Ribosomal and Transfer RNAs

    11.4. Synthesis and Structure of Eukaryotic Messenger RNAs

    11.5. Small Regulatory RNAs and RNA Silencing Pathways

    11.6. Green Cells: Long-Range siRNA Movement

    11.7. CRISPR and Other Noncoding RNAs

    11.8. Encoding Genetic Information

    11.9. Decoding the Codons: The Role of Transfer RNAs

    11.10. Translating Genetic Information

    11.11. Engineering Linkage: DNA Origami Analytic Questions

    Chapter 12: Control of Gene Expression
    12.1. Control of Gene Expression in Bacteria
    12.2. Engineering Linkage: Building Digital Logic with Genes
    12.3. Structure of the Nuclear Envelope
    12.4. Chromosomes and Chromatin
    12.5. The Nucleus as an Organized Organelle
    12.6. An Overview of Gene Regulation in Eukaryotes
    12.7. Transcriptional Control
    12.8. Green Cells: The ABC Model and MADS Domain Transcription Factors
    12.9. RNA Processing Control
    12.10. Translational Control
    12.11. Posttranslational Control: Determining Protein Stability Analytic Questions

    Chapter 13: DNA Replication and Repair
    13.1. DNA Replication
    13.2. DNA Replication in Bacterial Cells
    13.3. The Structure and Functions of DNA Polymerases
    13.4. Replication in Viruses
    13.5. Engineering Linkage: Storing Data in DNA
    13.6. DNA Replication in Eukaryotic Cells
    13.7. DNA Repair
    13.8. Green Cells: Gamma Gardens
    13.9. Between Replication and Repair Analytic Questions

    Chapter 14: Cell Division
    14.1. The Cell Cycle
    14.2. M Phase: Mitosis and Cytokinesis
    14.3. Engineering Linkage: The Role of Membrane Tension in Cell Division
    14.4. Green Cells: Unique Aspects of Plant Cell Division
    14.5. Meiosis Analytic Questions

    Chapter 15: Cell Signaling and Signal Transduction: Communication between Cells
    15.1. The Basic Elements of Cell Signaling Systems
    15.2. A Survey of Extracellular Messages and Their Receptors
    15.3. G Protein-Coupled Receptors and Their Second Messengers
    15.4. Engineering Linkage: Biosensors in Medicine and Biology
    15.5. Protein-Tyrosine Phosphorylation as a Mechanism for Signal Transduction
    15.6. Green Cells: Auxin Signaling
    15.7. The Role of Calcium as an Intracellular Messenger
    15.8. Convergence, Divergence, and Cross-Talk among Different Signaling Pathways
    15.9. The Role of NO as an Intracellular Messenger
    15.10. Apoptosis (Programmed Cell Death) Analytic Questions

    Chapter 16: Cancer
    16.1. Basic Properties of a Cancer Cell
    16.2. The Causes of Cancer
    16.3. Cancer: A Genetic Disorder
    16.4. Engineering Linkage: Therapeutic Radiation
    16.5. Green Cells: Plant-Based Chemotherapies
    16.6. Strategies for Combating Cancer

    Chapter 17: The Immune Response
    17.1. An Overview of the Immune Response
    17.2. Green Cells: The Plant Immune System
    17.3. The Clonal Selection Theory as It Applies to B Cells
    17.4. T Lymphocytes: Activation and Mechanism of Action
    17.5. Selected Topics on the Cellular and Molecular Basis of Immunity
    17.6. Engineering Linkage: Adoptive T-Cell Therapy
    17.7. Signal Transduction Pathways in Lymphocyte Activation

    Chapter 18: Techniques in Cell and Molecular Biology
    18.1. The Light Microscope
    18.2. Transmission Electron Microscopy
    18.3. Scanning Electron and Atomic Force Microscopy
    18.4. The Use of Radioisotopes
    18.5. Cell Culture
    18.6. The Fractionation of a Cell’s Contents by Differential Centrifugation
    18.7. Isolation, Purification, and Fractionation of Proteins
    18.8. Determining the Structure of Proteins and Multisubunit Complexes
    18.9. Fractionation of Nucleic Acids
    18.10. Nucleic Acid Hybridization
    18.11. Chemical Synthesis of DNA
    18.12. Recombinant DNA Technology
    18.13. Enzymatic Amplification of DNA by PCR
    18.14. DNA Sequencing
    18.1.5 DNA Libraries
    18.16. DNA Transfer into Eukaryotic Cells and Mammalian Embryos
    18.17. Gene Editing and Silencing
    18.18. The Use of Antibodies Additional Readings Glossary Index End User License Agreement

  • Citar Libro
    • Título: Karp´s Cell and Molecular Biology Concepts and Experiments
    • Autor/es:
    • ISBN-10: 1119598249
    • ISBN-13: 9781119598244
    • Edición: 9na Edición
    • Año de edición: 2020
    • Tema: Biología
    • Subtema: Biología Celular
    • Tipo de Archivo: eBook | Manual de Laboratorio | Solucionario (Premium)
    • Idioma: eBook en Inglés | Solucionario en Inglés

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