Introduction to Biomedical Engineering – John Enderle, Susan M. Blanchard, Joseph Bronzino – 2nd Edition

Dedication
Preface
Acknowledgements
Contributors To The First Edition
Contributors To The Second Edition

1. Biomedical Engineering: A Historical Perspective
1.1 Evolution Of The Modern Health Care System
1.2 The Modern Health Care System
1.3 What Is Biomedical Engineering
1.4 Roles Played By Biomedical Engineers
1.5 Professional Status Of Biomedical Engineering
1.6 Professional Societies
Exercises
References And Suggested Reading

2. Moral And Ethical Issues
2.1 Morality And Ethics: A Definition Of Terms
2.2 Two Moral Norms: Beneficence And Nonmaleficence
2.3 Redefining Death
2.4 The Terminally Ill Patient And Euthanasia
2.5 Taking Control
2.6 Human Experimentation
2.7 Definition And Purpose Of Experimentation
2.8 Informed Consent
2.9 Regulation Of Medical Device Innovation
2.10 Marketing Medical Devices
2.11 Ethical Issues In Feasibility Studies
2.12 Ethical Issues In Emergency Use
2.13 Ethical Issues In Treatment Use
2.14 The Role Of The Biomedical Engineer In The Fda Process
Exercises
Suggested Reading

3. Anatomy And Physiology
3.1 Introduction
3.2 Cellular Organization
3.3 Tissues
3.4 Major Organ Systems
3.5 Homeostasis
Exercises
Suggested Reading

4. Biomechanics
4.1 Introduction
4.2 Basic Mechanics
4.3 Mechanics Of Materials
4.4 Viscoelastic Properties
4.5 Cartilage, Ligament, Tendon, And Muscle
4.6 Clinical Gait Analysis
4.7 Cardiovascular Dynamics
Exercises
Suggested Reading

5. Rehabilitation Engineering And Assistive Technology
5.1 Introduction
5.2 The Human Component
5.3 Principles Of Assistive Technology Assessment
5.4 Principles Of Rehabilitation Engineering
5.5 Practice Of Rehabilitation Engineering And Assistive Technology
Exercises
Suggested Reading

6. Biomaterials
6.1 Materials In Medicine: From Prosthetics To Regeneration
6.2 Biomaterials: Properties, Types, And Applications
6.3 Lessons From Nature On Biomaterial Design And Selection
6.4 Tissue–Biomaterial Interactions
6.5 Guiding Tissue Repair With Bio-Inspired Biomaterials
6.6 Safety Testing And Regulation Of Biomaterials
6.7 Application-Specific Strategies For The Design And Selection Of Biomaterials
Exercises
Suggested Reading

7. Tissue Engineering
7.1 What Is Tissue Engineering?
7.2 Biological Considerations
7.3 Physical Considerations
7.4 Scaling Up
7.5 Implementation Of Tissue Engineered Products
7.6 Future Directions: Functional Tissue Engineering And The -Omics Sciences
7.7 Conclusions
7.8 Glossary
Exercises
Suggested Reading

8. Bioinstrumentation
8.1 Introduction
8.2 Basic Bioinstrumentation System
8.3 Charge, Current, Voltage, Power, And Energy
8.4 Resistance
8.5 Linear Network Analysis
8.6 Linearity And Superposition
8.7 Thévenin's Theorem
8.8 Inductors
8.9 Capacitors
8.10 A General Approach To Solving Circuits Involving Resistors, Capacitors, And Inductors
8.11 Operational Amplifiers
8.12 Time-Varying Signals
8.13 Active Analog Filters
8.14 Bioinstrumentation Design
Exercises
Suggested Reading

9. Biomedical Sensors
9.1 Introduction
9.2 Biopotential Measurements
9.3 Physical Measurements
9.4 Blood Gases And Ph Sensors
9.5 Bioanalytical Sensors
9.6 Optical Biosensors
Exercises
Suggested Reading

10. Biosignal Processing
10.1 Introduction
10.2 Physiological Origins Of Biosignals
10.3 Characteristics Of Biosignals
10.4 Signal Acquisition
10.5 Frequency Domain Representation Of Biological Signals
10.5.5 Properties Of The Fourier Transform
10.6 Linear Systems
10.7 Signal Averaging
10.8 Wavelet Transform And Short-Time Fourier Transform
10.9 Artificial Intelligence Techniques
Exercises
Suggested Reading

11. Bioelectric Phenomena
11.1 Introduction
11.2 History
11.3 Neurons
11.4 Basic Biophysics Tools And Relationships
11.5 Equivalent Circuit Model For The Cell Membrane
11.6 Hodgkin-Huxley Model Of The Action Potential
11.7 Model Of The Whole Neuron
Exercises
Suggested Reading

12. Physiological Modeling
12.1 Introduction
12.2 Compartmental Modeling
12.3 An Overview Of The Fast Eye Movement System
12.4 Westheimer Saccadic Eye Movement Model
12.5 The Saccade Controller
12.6 Development Of An Oculomotor Muscle Model
12.7 A Linear Muscle Model
12.8 A Linear Homeomorphic Saccadic Eye Movement Model
12.9 A Truer Linear Homeomorphic Saccadic Eye Movement Model
12.10 System Identification
Exercises
Suggested Reading

13. Genomics And Bioinformatics
13.1 Introduction
13.2 Core Laboratory Technologies
13.3 Core Bioinformatics Technologies
13.4 Conclusion
Exercises
Suggested Reading

14. Computational Cell Biology And Complexity
14.1 Computational Biology
14.2 The Modeling Process
14.3 Bionetworks
14.4 Introduction To Complexity Theory
Exercises
Suggested Reading

15. Radiation Imaging
15.1 Introduction
15.2 Emission Imaging Systems
15.3 Instrumentation And Imaging Devices
15.4 Radiographic Imaging Systems
Exercises
Suggested Reading

16. Medical Imaging
16.1 Introduction
16.2 Diagnostic Ultrasound Imaging
16.3 Magnetic Resonance Imaging (Mri)
16.4 Comparison Of Imaging Modes
Exercises
Suggested Reading

17. Biomedical Optics And Lasers
17.1 Introduction To Essential Optical Principles
17.2 Fundamentals Of Light Propagation In Biological Tissue
17.3 Physical Interaction Of Light And Physical Sensing
17.4 Biochemical Measurement Techniques Using Light
17.5 Fundamentals Of Photothermal Therapeutic Effects Of Lasers
17.6 Fiber Optics And Waveguides In Medicine
17.7 Biomedical Optical Imaging
Exercises
Suggested Reading

Appendix
A.1 Matlab
A.2 Solving Differential Equations Using Matlab
A.3 Block Diagrams And Simulink
A.4 Simulink